It does matter that some women do have to go through these things, in the cause of extreme inclusivity.
And in this discussion, it's naive to think that a man who transitions and smashes women at college sports—that these women poured their lives into—is just that thing in itself.
a) Should this bar FtM trans people from playing in male sports?
b) Is the MtF playing in women's sports on hormones, and if so for how long and at what measurement?
c) How many trans people who play for the opposite sex suddenly find themselves dominating?
Even without hormones in my system, even when I was at my peak physical performance, they would kick my ass.
As a tentative solution, I would suggest handling sports by weight class rather than gender.
Stuff like that is obviously representative of a direction the entire culture is being steered toward, which is bringing along with it all sorts of concepts like misgendering, microaggression, toxic masculinity, and so-on.
Misgendering:
Plenty of trans people find how pissed off people within their community can become over it to be Twitter-levels of cringe. When misgendering is done harmfully, it is done as such when the cis person speaking is insisting trans people are not as the gender they identify as, stubbornly, rather than accidently adding or dropping an 'S' into the gender label a few times.
It's the difference between "But you're a man" and "She... err, uh, he is doing things". The latter shows they made a mistake, mistakes happen, while the former is the misgender-er insisting on debating something the trans person is tired of having thrown at them so declaratively.
Once again I find this comparable to instances that cropped up during the fight for gay rights. It's one thing for someone to accidently project their own straight expectations onto the choices a gay person is making, and then notice and 'whoops' about it, while it's another to insist that gay people have simply "made the wrong choice", rather than being born with the proclivity, even going as far as to insist gay people must have undergone some sort of trauma to come to that conclusion, or sending them to straight camps to "fix it" over it being "unnatural".
Microaggression:
It depends on if they are leaning towards dogwhistle language, or if they have simply grown up a certain way and find themselves struggling to drop habits. Someone raised in a rich family for example might treat poor people as second class citizens, and that can be very annoying for said poor people to deal with.
People within the LGBTQ have varying levels of tolerance for it based on whatever events happened in their lives leading up to now, and while I am thankful enough to have been raised early within California sensibilities to the point of not having as large a queue of other people's intollerance that is not true for many others who have become triggerable over familiar patterns.
Those who are prone to reacting with unideal microaggressions should be sympathized with for it when it is the formative versions, but when it's stubborn attempts to conceal their own language as to not get in trouble while still speaking of an intolerance they fully believe in then that's more purposeful.
Even for my own situation, as a mild example I tend to crossdress less over not wanting people to look at me in a leery way. While that is how I'd prefer to look at points, I don't want to feel judged by those around me which in turn stifles the behavior while the tendency or desire remains. They don't really have to say anything if it's all over their faces, and those looks can make people like myself feel uncomfortable.
While I would not be so bold as to insist someone stop looking at me a certain way, since that's like, literal think policing, I can understand why someone bolder might protest being stared at wrongly just as much as "normies" can find it uncomfortable if and when it happens to them (like if they have a wet spot on the crotch of their pants or something). It's similar in nature to being the only white person in an all asian school, or the only black person walking in an all white neighborhood, except it's over something less physically apparent at first glance.
Toxic Masculinity:
I see a lot of people use this phrase to mean different things.
In the sense of it meaning "ingrained behaviors within male culture that stigmatize others", I think it makes sense to question and reform what those values are. Seeing for example women allowed to emote while men are not could have a man begin to envy women for that freedom, and when within a culture that does not accept male outcries beyond that of authoritative anger you'll see a lot of burying of their emotions to the point of stress accumulation and shorter lifespans.
Toxic Masculinity is literally killing them.
It's not true that people are just overreacting to extreme cases and outliers, when these are obviously the most clear breaking points of a massive cultural shift that is happening right in front of us.
Again this is like the "we can't just let people marry whatever they want" argument vs homosexuality.
What is happening is readily apparent in everyday life, from how actors are cast now, to what kind of language will get you kicked from school or fired.
Now THIS I would say is it's own can of worms, but from the other side of it.
There is good media that otherwise reflects leftist views, but then there's ones that ram it down your throat like an afterschool special. Even those who this media is supposed to be catering to can find it distasteful as a matter of quality, rather than the subject itself.
No one wants to see the group they're a part of presented in a cringey light, and a lot of the media meant to cater to the left without understanding it demonstrates the same issues we're seeing with Disney: Their black people feel white-scripted, their trans and gay expressions feel straight-scripted, and by the end of it you end up with preachy tokenism rather than an organic display of their characteristics.
It's like how someone who doesn't do drugs could still find the D.A.R.E. program cringe.
Edit: As for the getting people fired angle, it's worth looking at each case individually, otherwise you end up lumping the ones who simply made a mistake with those who defiantly refuse to tow the line. It's already been this way, but what changed was what subjects have been added to the taboo list.
If someone is outright preaching intolerance towards children, that's potentially concerning.