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Cannabinoid System Toll-Like Receptors Controls Inflammation


Posts: 2377

For all you weed smokers. Just know you are modulating your immune system.

 

Interaction between Cannabinoid System and Toll-Like
Receptors Controls Inflammation

Kathleen L. McCoy

Department of Microbiology and Immunology, Virginia Commonwealth University

 

Because all immune cells examined so far express
cannabinoid receptors regardless of their cell lineage, all
types of immunity are sensitive to cannabinoid modulation

 

In terms of adaptive immunity, cannabinoids usually
suppress primary antibody responses to T cell-dependent
antigens, induction of cytotoxic CD8 + T cells, and cytokine
production by helper CD4 + T cells, whereas other adaptive
immune responses are unaffected or enhanced

 

Furthermore, cannabi-noids impact innate immunity that mediates inflamma-
tory responses and promotes initiation of adaptive immune
responses.

 

 

This can be good or bad.

FEAR! FEAR! FEAR! FEAR! FEAR! FEAR!
last edit on 6/28/2022 5:35:17 AM
Posts: 2377
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

For many years, one puzzling aspect of innate immunity
has been inflammatory responses in the absence of an infec-
tion that contribute to tissue damage during autoimmune
diseases and chronic inflammatory diseases.

Cannabinoids directly impair TLR-induced cell activa-
tion in culture (Table 1). Δ 9 -Tetrahydrocannabinol perturbs
posttranslational processing of tumor necrosis factor-α pro-
tein in LPS-activated mouse macrophages [99, 100]. Fur-
thermore, cannabinoids diminish proinflammatory cytokine
production in LPS-stimulated mouse microglial BV-2 cell line
that is accompanied by decreased transcription factor NF-
κB activity and corresponding cytokine mRNA levels

 

In simple terms, Cannabinoids can reduce inflammation due to autoimmune
diseases and chronic inflammatory diseases

 

FEAR! FEAR! FEAR! FEAR! FEAR! FEAR!
Posts: 2474
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

Sounds like a good thing.

Posts: 354
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

The magical plant that brings us closer to God does it again.

Posts: 33432
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

If you only look at the best anything has to offer anything will look good. 

This would be like if I made the topic about how caffeine boosts the immune system. 😆

Ę̵̚x̸͎̾i̴͚̽s̵̻͐t̷͐ͅe̷̯͠n̴̤̚t̵̻̅i̵͉̿a̴̮͊l̵͍̂ ̴̹̕D̵̤̀e̸͓͂t̵̢͂e̴͕̓c̸̗̄t̴̗̿ï̶̪v̷̲̍é̵͔
Posts: 2474
1 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

If you only look at the best anything has to offer anything will look good. 

This would be like if I made the topic about how caffeine boosts the immune system. 😆

 Lol there are no down sides to weed. I guess the average weed smoker same age has a lower income than a person that doesn’t smoke, there is something to be said about that. It’s not really the cheapest habit either if you’re not growing a lot of it. It’s obviously a miracle drug.

Posts: 796
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

If you only look at the best anything has to offer anything will look good. 

This would be like if I made the topic about how caffeine boosts the immune system. 😆

 Go ahead and make a topic claiming how caffeine boosts the immune system then, and you'll see how it really goes.

Posts: 2377
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

If you only look at the best anything has to offer anything will look good. 

This would be like if I made the topic about how caffeine boosts the immune system. 😆

The point of this thread is that weed reduces your immune system, not boost. For some with allergies and autoimmune issues, a reduction is needed. Don't know if you picked up on that.

Weed could make you more susceptible to some viral or bacterial infections.

Caffeine is a drug also. Coffee, tea and other plants could boost the immune system. Or maybe they down regulate. Don't know. Mushrooms have also been shown to modulate the immune system upwards.

Vaccinated people should be listening to this.

 

FEAR! FEAR! FEAR! FEAR! FEAR! FEAR!
Posts: 2474
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation
LiYang said: 

If you only look at the best anything has to offer anything will look good. 

This would be like if I made the topic about how caffeine boosts the immune system. 😆

The point of this thread is that weed reduces your immune system, not boost. For some with allergies and autoimmune issues, a reduction is needed. Don't know if you picked up on that.

Weed could make you more susceptible to some viral or bacterial infections.

Caffeine is a drug also. Coffee, tea and other plants could boost the immune system. Or maybe they down regulate. Don't know. Mushrooms have also been shown to modulate the immune system upwards.

Vaccinated people should be listening to this.

 

I just don’t think that’s true. Also weed prevents and cures Covid.

Posts: 796
0 votes RE: Cannabinoid System Toll-Like Receptors Controls Inflammation

A non biased report.

In moderation I'd say it's fine. No reported cases of death from cannabis usage to date. Too much of anything isn't good.

Even drinking too much water will cause detox poisoning and be fatal.

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