I am lazy, so I'm just going to super-layman it for now. It's a core part of the struggle for trans-types right now and, regardless of your opinion over it, it's led to an interesting dialogue on the nature of gender.
Estrogen is on average higher in women while Testosterone is usually higher in men, and as we've seen with steroid use and medications there are not just physical changes in a person, but also their brain chemistry, how they process their thoughts, the behaviors they suddenly find themselves doing more naturally compared to before.
The traits of Testosterone tend to make a person less prone to asking questions in favor of pursuing their own internal goals, showing a reduction in the room to compromise with higher rates of aggression. You can see the gray area fade in their thinking as it more often splits into two camps of thinking, Us vs Them, survival junk. You also see drops in inhibition, they are more prone to just acting on their feelings rather than holding back or thinking about it first, becoming more prone to impulse. With socializing they tend to challenge people more and when Fight or Flight is triggered they are less likely to run.
By contrast there's the traits of Estrogen, which tend to make a person more prone to asking questions and looking into the smaller details, but with that comes the increased odds of hesitation and analysis paralysis, and from having to focus on so much more at a time they can undergo stress more easily. Compromise comes more naturally to Estrogen over how it makes a person more prone to patience and seeing the degrees of seperation, the gray area, rather than a quick decisive binary answer. Restraint increases as does a sense of defensiveness and fear, which is why Red Pill suggests men seek out hairier women if they are just looking to get laid. When socializing they tend to listen and try to see where they fit into the bigger picture rather than treating themselves as the bigger picture, and for Fight or Flight situations they tend to notice the danger first and prefer to find a vantage point to plan how to handle the problem, rather than charging straight at it, such as how women tend to be better at spotting avalanches than men on average.
Interestingly you can see the increase vs decrease in confidence between the two as expression something similar to the Dunning Kruger principal, likely accounting for why men keep finding themselves in leadership positions across history in spite of on average simpler thinking. While the two tend to have a balance in people, there's usually a higher amount of one than the other in a person that accounts for their behaviors reflecting one set as predominant.
Now where this gets interesting: People presume gender values and norms largely off of the symptoms of Estrogen and Testosterone having averages that conform to the gender divide: Higher T for dudes and higher E for chicks, but as we're becoming more able to see someone's T vs E counts and even steer them with drugs we're seeing people's behaviors begin to shift towards the other set of presumed stereotypes if not explain pre-existing dispositions. Even from cases of steroids gone wrong where the body pumps out waaaay too much Estrogen to try to balance it out, or Menopause where there's a sudden drop in Estrogen suddenly, you can see drastic shifts in a person's behavior.
Even something as simple as not being the first born son of the family, on average, lowers their Testosterone expression with each following male, and you can see symptoms of this within things like softer cheekbones and lower aggression.
Ę̵̚x̸͎̾i̴͚̽s̵̻͐t̷͐ͅe̷̯͠n̴̤̚t̵̻̅i̵͉̿a̴̮͊l̵͍̂ ̴̹̕D̵̤̀e̸͓͂t̵̢͂e̴͕̓c̸̗̄t̴̗̿ï̶̪v̷̲̍é̵͔
